Oregon and USC are Big Ten opponents. This page tracks how sportsbooks have priced their meetings: where the line opened, how it moved, how far prices differed between books and how each game finished. OddsBay records every price from the first line to kickoff, and we add each new meeting to the record below.

Oregon vs USC: the OddsBay record

Lines are the median price across the sportsbooks OddsBay tracks. “Open” is the first widely available line, about a week before kickoff, and “Close” is the line at kickoff.

September 26, 2026: Oregon at USC

  • Spread: USC −1.5 at open, Oregon −3.5 at close
  • Total: 61.5 at open, 61.5 at close
  • Final: Oregon 41, USC 27
  • Result: Oregon −3.5 covered; the game went over (68 points)
Line chart of the Oregon spread before the Sep 26, 2026 game, from +1.5 to −3.5 at the close
Oregon spread before the September 26, 2026 meeting, median of the sportsbooks tracked by OddsBay. Final: Oregon 41, USC 27; Oregon −3.5 covered.

Next meeting

Conference schedules rotate, so these teams do not necessarily play every season. This page will be updated when they meet again. Compare live college football prices on the OddsBay price finder.

How the last meeting was priced

USC opened as a 1.5-point home favorite. By three days out the line had flipped to Oregon −3, and it closed at Oregon −3.5, a move of five points toward the visitors. The total stayed at 61.5.

Oregon won 41–27, covering by 10.5, and the 68 points went over. Here the market move pointed the right way. Oregon closed around −175, an implied chance of about 64%.

Our guides to line movement and implied probability explain how to read these numbers.

Line shopping in this matchup

At kickoff, OddsBay tracked moneyline prices from 38 sportsbooks:

  • Oregon moneyline (won): from −189 at the worst book to −150 at the best. A winning $100 bet paid $14 more at the best price.
  • USC moneyline: from +122 to +160.
  • The spread: 28 books closed at 3.5 and 4 at 3. An Oregon bettor at −3 had a half point of protection that most of the market did not offer.
Chart of moneyline prices at kickoff across sportsbooks: Oregon (won) from −189 to −150; USC from +122 to +160
Worst and best moneyline prices at kickoff on September 26, 2026, across the sportsbooks tracked by OddsBay.

College football prices tend to vary more between books than NFL prices. Our line shopping guide shows how to compare them, and the vig guide explains why books differ.

What makes Oregon vs USC different to bet

  • Key numbers matter less. In 549 college football games OddsBay recorded, 3 was the most common margin (9.5%) and 7 the second (7.1%), but 40% of games were decided by 21 or more. Half points around 3 and 7 still count, just less than in the NFL. See our college football key numbers guide.
  • Home field is already in the price. Home teams won 63.5% of 543 college football games we recorded but covered the spread only 50.7% of the time. Our guide to home-field advantage explains why.
  • Rankings are not prices. Favorites won 76.9% of 545 games we recorded but covered only 46.7%. See rankings vs betting markets and our guide to rivalry games.
  • High-scoring matchups. A total above 60 means points come in bunches and margins can stretch late. Spreads in high-total games move less around single key numbers.

What to check before the next meeting

  1. Quarterbacks and injuries. Confirm who is starting and which key players are out.
  2. Weather. For outdoor games, check the wind forecast for game day.
  3. Where the line sits. Note what each half point costs.
  4. Prices across books. Compare the moneyline, spread and total on the odds comparison before betting.
  5. Your bet against the close. After the game, compare the price you took with the closing line. Our guide to the closing line explains why.

More college football matchup guides

Big Ten: Iowa vs Michigan, Ohio State vs Iowa, Iowa vs Washington, USC vs Penn State, Washington vs USC

SEC: Georgia vs Alabama, Auburn vs Tennessee, Ole Miss vs Florida, Texas A&M vs LSU, Texas vs Oklahoma, Texas vs Tennessee

Big 12: Iowa State vs BYU, BYU vs TCU

ACC: Miami vs Clemson

Betting responsibly

Rivalry games attract emotional bets. Decide your stake in advance (our guide to bankroll management shows how) and treat betting as entertainment. If gambling stops being fun, help is available: in the United States, the National Problem Gambling Helpline is available 24/7 by calling or texting 1-800-MY-RESET.

Key takeaways

  • Oregon and USC are Big Ten opponents; their meetings depend on the conference schedule.
  • Before the September 26, 2026 meeting, the line moved from USC −1.5 to Oregon −3.5; Oregon won 41–27 and the game went over 61.5.
  • The Oregon moneyline ranged from −189 to −150 across 38 books at kickoff.

Frequently asked questions

Who won the last Oregon vs USC game?

Oregon beat USC 41–27 on September 26, 2026, covering as a 3.5-point road favorite in Los Angeles. This page is updated after each meeting.

Do Oregon and USC play every year?

Not necessarily. Conference schedules rotate, so check the current schedule. When they meet again, we add the game to the record on this page.