The 49ers and Seahawks are NFC West rivals, so they play twice every regular season, once in San Francisco and once in Seattle. This page tracks how sportsbooks have priced each meeting: where the line opened, how it moved, how far prices differed between books and how the game finished. OddsBay records every price from the first line to kickoff, and we add each new meeting to the record below.

49ers vs Seahawks: the OddsBay record

Lines are the median price across the sportsbooks OddsBay tracks. “Open” is the first line we recorded and “Close” is the line at kickoff.

October 11, 2026: 49ers at Seahawks

  • Spread: Seahawks −3.5 at open, −3 at close
  • Total: 47.5 at open, 46.5 at close
  • Final: 49ers 32, Seahawks 29
  • Result: 49ers +3 covered and won outright; the game went over (61 points)
Line chart of the Seahawks spread before the October 11, 2026 game, moving from −3.5 to −3
Seahawks spread before the October 11, 2026 meeting, median of the sportsbooks tracked by OddsBay. Final: 49ers 32, Seahawks 29; 49ers +3 covered; Over 46.5.

November 29, 2026: Seahawks at 49ers

Upcoming. Compare live prices on the OddsBay price finder.

How the October meeting was priced

Seattle opened as a 3.5-point home favorite. By three days before kickoff the median had dropped to the key number of 3, and it stayed there. The total slipped a point, from 47.5 to 46.5.

San Francisco won 32–29, so the 49ers covered as 3-point underdogs and won outright. Seattle closed around −165 on the moneyline, which implied roughly a 62% chance of winning. The teams scored 61 points, 14.5 over the closing total. Our guides to line movement and implied probability explain how to read those numbers.

Line shopping in this matchup

At kickoff, OddsBay tracked moneyline prices from 45 sportsbooks, and the spread was not the same everywhere:

  • 49ers moneyline: from +118 at the worst book to +145 at the best. A winning $100 bet paid $27 more at the best price.
  • Seahawks moneyline: from −189 to −145.
  • The spread: 26 books closed at 3 and 8 at 3.5. Bettors who wanted the 49ers at +3.5 paid for it, at −125 to −155.
Chart of moneyline prices at kickoff across sportsbooks: 49ers (won) from +118 to +145; Seahawks from −189 to −145
Worst and best moneyline prices at kickoff on October 11, 2026, across the sportsbooks tracked by OddsBay.

Our line shopping guide shows how to compare prices, and the vig guide explains why books differ.

What makes 49ers vs Seahawks different to bet

  • Division familiarity. The teams play twice a year and know each other’s schemes. In the first five weeks of the 2026 season, OddsBay recorded 22 NFL division games: the underdog covered the closing spread in 15 and won outright in 12. In non-division games, underdogs covered 25 of 53. Twenty-two games is a small sample, so treat this as context, not a system.
  • Key numbers. In the 79 NFL games OddsBay recorded in the first five weeks, 3 was the most common final margin (15.2% of games) and 7 the second (10.1%). When a line sits near 3 or 7, the half point and its price matter. Our point spread guide covers the basics.
  • Two very different stadiums. Seattle is one of the loudest road environments in the league, which is part of why the home side is usually priced with a few points of home-field advantage. The market builds that in before you bet.
  • Late-season weather. The second meeting often falls in late November or later. Rain and wind in Seattle can matter more than cold, so check the forecast close to kickoff. See our guide to over/under betting.

What to check before the next meeting

  1. Quarterbacks and injuries. Confirm who is starting and which key players are out.
  2. Weather. For outdoor games, check the wind forecast for game day.
  3. Where the line sits relative to 3 and 7. Note what each half point costs.
  4. Prices across books. Compare the moneyline, spread and total on the odds comparison before betting.
  5. Your bet against the close. After the game, compare the price you took with the closing line. Our guide to the closing line explains why.

More NFL division matchup guides

Betting responsibly

Rivalry games attract emotional bets. Decide your stake in advance (our guide to bankroll management shows how) and treat betting as entertainment. If gambling stops being fun, help is available: in the United States, the National Problem Gambling Helpline is available 24/7 by calling or texting 1-800-MY-RESET.

Key takeaways

  • The 49ers and Seahawks meet twice every regular season as NFC West rivals.
  • In the October 11, 2026 meeting, the spread moved from Seahawks −3.5 to −3 and the total from 47.5 to 46.5; the 49ers won 32–29 and the game went over.
  • The 49ers moneyline ranged from +118 to +145 across 45 books at kickoff.
  • With the line on 3, the half point to 3.5 cost bettors a lot of juice.

Frequently asked questions

How often do the 49ers and Seahawks play?

Twice every regular season, once in each city, because they are in the same division. They can also meet in the playoffs.

Who won the last 49ers vs Seahawks game?

The 49ers won the October 11, 2026 meeting 32–29 in Seattle as 3-point underdogs. This page is updated after each meeting.

Why was +3.5 so much more expensive than +3?

Three is the most common margin in the NFL, so the half point from 3 to 3.5 protects against many results. Books charge for it.